Opportunity Information: Apply for PA 16 427
The Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R01) funding opportunity (PA-16-427) is a National Institutes of Health (NIH) discretionary grant program designed to support research that improves how symptoms are prevented, recognized, and treated in people living with HIV who are also dealing with additional health problems. The central focus is on older adults with long-term HIV infection, a group that increasingly faces complex symptom burdens tied not only to HIV itself, but also to HIV-associated Non-AIDS conditions (often referred to as HANA) and other comorbidities that can develop or worsen with aging and prolonged infection. The intent is to move beyond basic descriptions of symptoms and instead fund practical, research-tested approaches that lead to better real-world symptom control and quality of life.
A key theme of this opportunity is innovation paired with cost-effectiveness. Proposed projects are expected to develop, adapt, and test strategies that are feasible to implement in clinical or community settings and that make sense in terms of cost, scalability, and sustainability. The emphasis on symptom management means applicants can propose interventions that help prevent symptoms before they occur, improve early identification and monitoring of symptom patterns, or strengthen clinical and supportive care responses once symptoms appear. Because the targeted population often experiences multiple overlapping conditions, the program is oriented toward approaches that work in the presence of comorbidity rather than assuming a single-disease model. In practical terms, this could include research on new care models, screening and assessment tools, behavioral or supportive interventions, care coordination approaches, technology-assisted symptom tracking, or other strategies aimed at reducing symptom severity, frequency, or impact on daily functioning.
The grant mechanism is the NIH R01, which is commonly used for substantial, hypothesis-driven research projects and typically supports multi-year studies with clearly defined aims, rigorous methods, and meaningful outcomes. The activity category is Education and Health, and the Catalog of Federal Domestic Assistance (CFDA) number associated with this opportunity is 93.361. While the award ceiling and expected number of awards are not specified in the provided source data, the R01 format signals an expectation for well-developed research plans, appropriate study designs (for example, intervention development followed by pilot testing or full-scale trials as appropriate), and strong analytic approaches that can demonstrate whether a symptom management strategy works and for whom it works best.
Eligibility for this opportunity is broad, reflecting NIH's interest in drawing solutions from many sectors. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; and a wide range of nonprofit organizations, including both 501(c)(3) and non-501(c)(3) entities (excluding higher education institutions where specified). For-profit organizations (other than small businesses) and small businesses are also eligible, along with other applicant types. The opportunity also explicitly welcomes applications from organizations that serve or represent specific communities, including Alaska Native and Native Hawaiian Serving Institutions; Asian American, Native American, and Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; U.S. territories or possessions; eligible federal government agencies; and tribal governments that are not federally recognized. Non-domestic (non-U.S.) entities, meaning foreign organizations, are also listed as eligible, which highlights an openness to international perspectives and research settings where relevant.
The opportunity was created on 2016-09-08, and the original closing date listed in the source data is 2018-01-24. As framed, the program is meant to address a growing public health and clinical challenge: people with HIV are living longer, and many are managing multiple chronic conditions at once. This grant supports research aimed at producing practical symptom management strategies that can reduce suffering, improve functioning and well-being, and potentially lessen healthcare utilization by preventing symptoms from escalating into avoidable complications.Apply for PA 16 427
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361.
- This funding opportunity was created on 2016-09-08.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
[Watch] Creating a grant proposal using the step-by-step wizard inside the applicant portal:
Browse more opportunities from the same category: Education, Health
Next opportunity: NINDS Ruth L. Kirschstein National Research Service Award (NRSA) for Training of Postdoctoral Fellows (F32)
Previous opportunity: Fiscal Year 2016 Nonprofit Security Grant Program (NSGP)
Applicant Portal:
Are you interested in learning about about how to apply for this government funding opportunity? You can create a free applicant account and receive instant access to our applicant portal that many business owners like you have benefited from.
Apply for PA 16 427
Applicants also applied for:
Applicants who have applied for this opportunity (PA 16 427) also looked into and applied for these:
| Funding Opportunity |
|---|
| Symptom Management in HIV-Infected Individuals with Comorbid Conditions (R21) Apply for PA 16 429 Funding Number: PA 16 429 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Encouraging Appropriate Care Using Behavioral Economics through Electronic Health Records (R21/R33) Apply for RFA AG 17 013 Funding Number: RFA AG 17 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Drug Abuse Dissertation Research (R36) Apply for PA 16 443 Funding Number: PA 16 443 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Improving the HIV Pre-Exposure Prophylaxis (PrEP) Cascade (R34) Apply for RFA MH 17 361 Funding Number: RFA MH 17 361 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Improving the HIV Pre-Exposure Prophylaxis (PrEP) Cascade (R01) Apply for RFA MH 17 360 Funding Number: RFA MH 17 360 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Multi-Site Pilot and Feasibility Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R34) Apply for PAR 16 456 Funding Number: PAR 16 456 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Multi-Site Studies for System-Level Implementation of Substance Use Prevention and Treatment Services (R01) Apply for PAR 16 455 Funding Number: PAR 16 455 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Collaborative Consortia for the Study of HIV Associated Cancers: U.S. and Low-and Middle-Income Country Partnerships (U54) Apply for RFA CA 16 018 Funding Number: RFA CA 16 018 Agency: National Institutes of Health Category: Education, Health Funding Amount: $600,000 |
| National Cancer Institute Program Project Applications (P01) Apply for PAR 16 457 Funding Number: PAR 16 457 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| International Research Scientist Development Award (IRSDA) (K01) Apply for PAR 17 002 Funding Number: PAR 17 002 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01) Apply for PAR 17 003 Funding Number: PAR 17 003 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Hepatitis C Virus (HCV) Advanced Molecular Detection in Support of Systems for Prevention, Treatment and Control of HIV, HCV and Related Comorbidities in Rural Communities Affected by Opioid Injection Drug Epidemics in the United States (U24) Apply for RFA DA 17 023 Funding Number: RFA DA 17 023 Agency: National Institutes of Health Category: Education, Health Funding Amount: $370,000 |
| HIV, HCV and Related Comorbidities in Rural Communities Affected by Opioid Injection Drug Epidemics in the United States: Building Systems for Prevention, Treatment and Control (UG3/UH3) Apply for RFA DA 17 014 Funding Number: RFA DA 17 014 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Use of Technology to Enhance Patient Outcomes and Prevent Illness (R21) Apply for PA 17 009 Funding Number: PA 17 009 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Improving Individual and Family Outcomes through Continuity and Coordination of Care in Hospice (R21) Apply for PA 17 015 Funding Number: PA 17 015 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Self-Management Interventions and Technologies to Sustain Health and Optimize Functional Capabilities (R01) Apply for PA 17 012 Funding Number: PA 17 012 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01) Apply for PA 17 014 Funding Number: PA 17 014 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R21) Apply for PA 17 013 Funding Number: PA 17 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Self-Management Interventions and Technologies to Sustain Health and Optimize Functional Capabilities (R21) Apply for PA 17 011 Funding Number: PA 17 011 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Improving Individual and Family Outcomes through Continuity and Coordination of Care in Hospice (R01) Apply for PA 17 016 Funding Number: PA 17 016 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
Grant application guides and resources
It is always free to apply for government grants. However the process may be very complex depending on the funding opportunity you are applying for. Let us help you!
Apply for Grants
Inside Our Applicants Portal
Access Applicants Portal
- Grants Repository - Access current and historic funding opportunities with ease. Thousands of funding opportunities are published every week. We can help you sort through the database and find the eligible ones to apply for.
- Applicant Video Guides - The grant application process can be challenging to follow. We can help you with intuitive video guides to speed up the process and eliminate errors in submissions.
- Grant Proposal Wizard - We have developed a network of private funding organizations and investors across the United States. We can reach out and submit your proposal to these contacts to maximize your chances of getting the funding you need.
Premium leads for funding administrators, grant writers, and loan issuers
Thousands of people visit our website for their funding needs every day. When a user creates a grant proposal and files for submission, we pass the information on to funding administrators, grant writers, and government loan issuers.
If you manage government grant programs, provide grant writing services, or issue personal or government loans, we can help you reach your audience.
Learn More
Request more information:
Would you like to learn more about this funding opportunity, similar opportunities to "PA 16 427", eligibility, application service, and/or application tips? Submit an inquiry below:
Don't forget to subscribe to our grant alerts mailing list to receive weekly alerts on new and updated grant funding opportunities like this one in your email.