Opportunity Information: Apply for CDC RFA JG 25 0074
This funding opportunity is a CDC cooperative agreement under PEPFAR focused on strengthening HIV and TB service delivery in Eswatini in a way that is person-centered, equitable, high-quality, and better integrated at the point of care. The program is intended to support site-level HIV/TB prevention, care, and treatment services while aligning closely with Eswatini's national vision for a sustainable HIV/TB response and PEPFAR's 2023-2028 Five-Year Strategy. The overall thrust is not just maintaining services, but improving how they are delivered, making them more responsive to patient needs, more consistent in quality, and more connected across clinical areas so clients experience a coordinated pathway rather than fragmented services.
Funding details are somewhat unusual at first glance: the posted Year 1 award ceiling is listed as 0 (none), but CDC anticipates an approximate total of $4,000,000 available in Fiscal Year funding for Year 1, contingent on the availability of funds. CDC expects to make about three awards. Because this is a cooperative agreement, applicants should expect substantial CDC involvement in planning, implementation support, and performance monitoring compared to a standard grant. The opportunity is listed as discretionary funding in the health category under CFDA 93.067, and it is broadly open to many applicant types, including government entities, public and private colleges and universities, nonprofits with or without 501(c)(3) status, for-profit organizations (including small businesses), tribal governments and organizations, and other unrestricted applicants.
Programmatically, the award is designed to reinforce both demand for services and the delivery of those services. On the demand side, that typically means strengthening approaches that help people seek and remain in care, reducing access barriers, and working with communities to improve awareness, trust, and uptake. On the delivery side, the work emphasizes implementing national guidelines correctly and consistently, fostering innovation in how services are organized and delivered, and pushing for practical integration of HIV and TB services at the facility level. Integration here implies that HIV and TB prevention, screening, diagnosis, treatment, follow-up, and support services should function as a cohesive package where possible, rather than being siloed into separate workflows that increase missed opportunities and patient burden.
A core expectation is continuous quality improvement and stronger use of data for decision-making. The opportunity highlights maintaining quality and improving effective data use, which often translates into strengthening routine monitoring, improving data completeness and timeliness, using data to identify gaps in coverage or performance, and acting on those insights through targeted mentorship and operational changes. It also signals that support may need to be hands-on and operational, not only technical. CDC specifically notes that more intensive logistical and technical support may be required to prevent service disruptions, particularly in higher-risk areas such as laboratory diagnostic services, commodity management (for example, ensuring test kits and medications are available when and where needed), and health information system implementation. In practice, this points to a strong emphasis on systems that keep clinics functioning reliably: supply chains, specimen transport and lab networks, inventory controls, and digital or routine reporting systems.
A major outcome built into the design of the notice of funding opportunity is a planned transition over the course of the award. The expectation is that the intensity of external support should gradually decrease as service delivery, key response functions, and clinical mentorship are transferred to the Ministry of Health and/or other local entities. That means applicants should be prepared to show how they will build local capacity from the start, shift responsibilities in a deliberate way, and avoid creating parallel systems that are difficult to sustain. Even though investments should prioritize HIV/TB interventions, CDC also signals that these investments should be adaptable to broader public health goals, suggesting a preference for strengthening platforms and capabilities (workforce, labs, data systems, supply chains, quality improvement) that can serve multiple health priorities over time.
Geographically, the work is expected to concentrate in the Manzini and Lubombo regions, but awardees must have the ability to operate across all regions as needed. The approach is also expected to be collaborative and community-informed. CDC explicitly calls for meaningful engagement with stakeholders, community organizations, beneficiaries, and affected communities, which indicates that community input should not be a box-checking exercise but a driver of how interventions are selected, tailored, and evaluated. This requirement fits with the person-centered and equitable framing of the opportunity, where services should reflect lived realities, address disparities, and respond to barriers faced by populations most affected by HIV and TB.
Key administrative details include the opportunity number CDC RFA JG 25 0074, with an original closing date of 2025-03-05 and a creation date of 2024-12-17. Overall, the opportunity is aimed at ensuring Eswatini's HIV/TB services remain resilient, integrated, and high-performing in the near term while deliberately moving toward local ownership and sustainability in line with national priorities and PEPFAR's strategy for 2023-2028.Apply for CDC RFA JG 25 0074
- The Centers for Disease Control-GHC in the health sector is offering a public funding opportunity titled "Supporting the provision of person-centered, equitable, high-quality, and integrated service delivery towards a sustainable and resilient HIV/TB response in the Kingdom of Eswatini under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on 2024-12-17.
- Applicants must submit their applications by 2025-03-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Unrestricted.
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Frequently Asked Questions (FAQs)
1) What is this funding opportunity?
This is a CDC cooperative agreement under PEPFAR focused on strengthening HIV and TB service delivery in Eswatini. The emphasis is on person-centered, equitable, high-quality services that are better integrated at the point of care.
2) What is the main goal of the program?
The main goal is to support and improve site-level HIV/TB prevention, care, and treatment services so they are more responsive to patient needs, more consistent in quality, and better connected across clinical areas. The intent goes beyond maintaining services and focuses on improving how services are delivered so clients experience a coordinated pathway rather than fragmented care.
3) How does this opportunity align with national and global strategies?
The program is intended to align closely with Eswatini's national vision for a sustainable HIV/TB response and with PEPFAR's 2023-2028 Five-Year Strategy.
4) What is the opportunity number and key dates provided?
The opportunity number is CDC RFA JG 25 0074. The creation date provided is 2024-12-17, and the original closing date provided is 2025-03-05.
5) What type of funding mechanism is this?
This is a cooperative agreement, which typically involves substantial CDC involvement in planning, implementation support, and performance monitoring compared to a standard grant.
6) What does "substantial CDC involvement" mean in practical terms?
Based on the description, applicants should expect CDC to be involved beyond routine grant oversight, including engagement in planning, implementation support, and monitoring performance as the program is carried out.
7) How much funding is expected to be available for Year 1?
The posted Year 1 award ceiling is listed as 0 (none). However, CDC anticipates an approximate total of $4,000,000 available in Fiscal Year funding for Year 1, contingent on the availability of funds.
8) Why does the Year 1 ceiling show as 0 if funding is anticipated?
The notice indicates an unusual presentation where the posted Year 1 award ceiling is 0, while CDC still anticipates approximately $4,000,000 in Year 1 Fiscal Year funding contingent on funds being available. The information provided does not explain the reason for the 0 ceiling, only that CDC anticipates Year 1 funding.
9) How many awards does CDC expect to make?
CDC expects to make about three awards.
10) What CFDA number and category are associated with this opportunity?
The opportunity is listed as discretionary funding in the health category under CFDA 93.067.
11) Who is eligible to apply?
The opportunity is described as broadly open to many applicant types, including:
- Government entities
- Public and private colleges and universities
- Nonprofits with or without 501(c)(3) status
- For-profit organizations (including small businesses)
- Tribal governments and organizations
- Other unrestricted applicants
12) What kinds of services or activities does the award aim to support?
The award is designed to reinforce both demand for services and the delivery of services. This includes strengthening approaches that help people seek and remain in care, reducing access barriers, and improving community awareness, trust, and uptake. It also includes improving service delivery through correct and consistent implementation of national guidelines, innovation in service organization, and practical integration of HIV and TB services at the facility level.
13) What does the opportunity mean by strengthening "demand" for HIV/TB services?
On the demand side, the description points to approaches that help people seek services and remain in care, reduce access barriers, and work with communities to improve awareness, trust, and uptake.
14) What does the opportunity emphasize on the "service delivery" side?
On the delivery side, the focus is on implementing national guidelines correctly and consistently, fostering innovation in how services are organized and delivered, and integrating HIV and TB services at the facility level.
15) What does "integration of HIV and TB services" mean in this context?
Integration is described as having HIV and TB prevention, screening, diagnosis, treatment, follow-up, and support services function as a cohesive package where possible. The goal is to avoid siloed workflows that create missed opportunities and increase burden on patients.
16) Is the program focused on maintaining existing services or improving them?
The thrust is explicitly not only maintaining services, but improving how services are delivered so they are more responsive to patient needs, more consistent in quality, and more connected across clinical areas.
17) What are the expectations related to quality improvement?
A core expectation is continuous quality improvement. The opportunity highlights maintaining quality and improving effective data use, which typically translates into stronger routine monitoring, better data completeness and timeliness, identifying gaps in coverage or performance, and acting on findings through targeted mentorship and operational changes.
18) What role does data play in this program?
The opportunity emphasizes stronger use of data for decision-making, including improving routine monitoring, data completeness and timeliness, using data to identify gaps, and using insights to drive mentorship and operational improvements.
19) What kinds of operational or logistical support does CDC anticipate may be needed?
CDC notes that more intensive logistical and technical support may be required to prevent service disruptions. Higher-risk areas mentioned include laboratory diagnostic services, commodity management (such as ensuring test kits and medications are available when and where needed), and health information system implementation.
20) What systems are implied as important for preventing service disruptions?
The description points to systems that keep clinics functioning reliably, including supply chains, specimen transport and lab networks, inventory controls, and digital or routine reporting systems.
21) What is the expected approach to sustainability and local ownership?
A major planned outcome is transition over the course of the award. The expectation is that external support will gradually decrease as service delivery, key response functions, and clinical mentorship are transferred to the Ministry of Health and/or other local entities. Applicants are expected to build local capacity from the start and avoid creating parallel systems that are difficult to sustain.
22) What does "transition" mean for an awardee's role over time?
Transition is described as a deliberate shift where the intensity of external support decreases and responsibilities are transferred to the Ministry of Health and/or other local entities. This includes shifting service delivery functions and clinical mentorship over time.
23) Does the opportunity encourage investments that have benefits beyond HIV/TB?
Yes. While investments should prioritize HIV/TB interventions, CDC signals that investments should be adaptable to broader public health goals, suggesting a preference for strengthening platforms and capabilities (workforce, labs, data systems, supply chains, quality improvement) that can serve multiple health priorities over time.
24) Where in Eswatini is the work expected to focus?
The work is expected to concentrate in the Manzini and Lubombo regions.
25) Is an awardee expected to operate outside Manzini and Lubombo?
Yes. While the work is expected to concentrate in Manzini and Lubombo, awardees must have the ability to operate across all regions as needed.
26) What does the opportunity say about collaboration and community engagement?
The approach is expected to be collaborative and community-informed. CDC explicitly calls for meaningful engagement with stakeholders, community organizations, beneficiaries, and affected communities, with community input serving as a driver of how interventions are selected, tailored, and evaluated.
27) How does the opportunity define "person-centered" and "equitable" service delivery?
The description frames the work around services that reflect lived realities, address disparities, and respond to barriers faced by populations most affected by HIV and TB, while ensuring care is coordinated and not fragmented.
28) What is the overall intended impact of this program?
The opportunity aims to ensure Eswatini's HIV/TB services remain resilient, integrated, and high-performing in the near term, while deliberately moving toward local ownership and sustainability in line with national priorities and PEPFAR's 2023-2028 strategy.
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| Strengthening comprehensive HIV and TB services and health systems in high-burden areas of Namibia under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0092 Funding Number: CDC RFA JG 25 0092 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Advancing country-led sustainable digital health transformation across PEPFAR-supported countries through informatics workforce capacity development to end HIV/AIDS and TB as a public health threat by 2030 under PEPFAR Apply for CDC RFA JG 25 0055 Funding Number: CDC RFA JG 25 0055 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Advancing national epidemiologic, surveillance, research and laboratory capacities and systems to support a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini under PEPFAR Apply for CDC RFA JG 25 0071 Funding Number: CDC RFA JG 25 0071 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Strengthening the technical capacity of the Ministry of Health to deliver a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini under PEPFAR Apply for CDC RFA JG 25 0073 Funding Number: CDC RFA JG 25 0073 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Strengthening the organizational capacity of the Ministry of Health to deliver a sustainable and resilient response to HIV/TB and related public health threats in the Kingdom of Eswatini under PEPFAR Apply for CDC RFA JG 25 0072 Funding Number: CDC RFA JG 25 0072 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Strengthening the Government of Namibia’s health information systems (HIS) to improve public health programs under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0093 Funding Number: CDC RFA JG 25 0093 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Supporting the implementation of comprehensive HIV prevention and treatment programs to achieve and sustain epidemic control in Zimbabwe under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0099 Funding Number: CDC RFA JG 25 0099 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Healthy Tomorrows Partnership for Children Program (HTPCP) Apply for HRSA 25 019 Funding Number: HRSA 25 019 Agency: Health Resources and Services Administration Category: Health Funding Amount: $75,000 |
| Pediatric Pulmonary Centers Program Apply for HRSA 25 026 Funding Number: HRSA 25 026 Agency: Health Resources and Services Administration Category: Health Funding Amount: $340,000 |
| Maternal and Child Health Secondary Data Analysis Research (MCH SDAR) Apply for HRSA 25 023 Funding Number: HRSA 25 023 Agency: Health Resources and Services Administration Category: Health Funding Amount: $60,000 |
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| Strengthening the national HIV care and treatment program in Sierra Leone (SL) to accelerate the response to end the HIV/AIDS pandemic as a public health threat by 2030, under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0060 Funding Number: CDC RFA JG 25 0060 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Combination prevention solutions to reach epidemic control among high risk, priority populations in high burden areas in South Africa (SA) under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0057 Funding Number: CDC RFA JG 25 0057 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Providing targeted technical assistance to the HIV/TB prevention-care-treatment continuum using cost efficient and scalable quality improvement approaches to address program gaps in support of sustainable HIV services in Zambia under PEPFAR Apply for CDC RFA JG 25 0062 Funding Number: CDC RFA JG 25 0062 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Capacity building and technical assistance for sustainable community-led monitoring (CLM) of HIV services in Sierra Leone (SL) under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0061 Funding Number: CDC RFA JG 25 0061 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Strengthening economic analysis and capacity in support of program management for HIV, TB, and related health threats in South Africa (SA) under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0056 Funding Number: CDC RFA JG 25 0056 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Strengthening and modernizing sustainable public health systems and workforce in Uganda for data science, informatics, surveys, and surveillance for timely, accurate, and integrated data for action under PEPFAR Apply for CDC RFA JG 25 0047 Funding Number: CDC RFA JG 25 0047 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Implement and sustain a comprehensive response to HIV and technical assistance to strengthen the capacity of regional authorities in the United Republic of Tanzania under the President's Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0095 Funding Number: CDC RFA JG 25 0095 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Provide technical assistance to the Botswana Ministry of Health to implement HIV/TB policies and services for children and adolescents living with HIV including mental health and psychosocial support and pregnant and breastfeeding women under PEPFAR Apply for CDC RFA JG 25 0083 Funding Number: CDC RFA JG 25 0083 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
| Provide technical assistance (TA) to support the Botswana Ministry of Health (MOH) implement policies and programs across the HIV clinical and prevention cascade under the President’s Emergency Plan for AIDS Relief (PEPFAR) Apply for CDC RFA JG 25 0082 Funding Number: CDC RFA JG 25 0082 Agency: Centers for Disease Control-GHC Category: Health Funding Amount: Case Dependent |
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