Opportunity Information: Apply for PA 23 189
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed), Funding Opportunity Number PA-23-189, is an NIH (and CDC-notified) administrative supplement program that provides add-on funds to existing, eligible NIH research grants so that current grantees can bring more people from diverse backgrounds into health-related research and support their training and career development. The basic idea is that the supplement is not a stand-alone grant for a brand-new project; it is extra support that must stay within the scientific scope of the already-funded parent award. Through these supplements, a funded lab or research team can recruit and support students, postdoctoral researchers, and certain eligible investigators, particularly individuals from groups that have been shown to be underrepresented in health-related research. In addition to the diversity-focused purpose, the program also covers a related need: it can provide supplemental support to a Program Director/Principal Investigator who has become disabled (or is disabled) and requires accommodations or other additional resources in order to continue working on the funded project.
A key restriction in this specific NOFO is the clinical trial limitation. This opportunity is structured for applicants who are not proposing to lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial under the supplement. In other words, you cannot use this administrative supplement to turn the parent grant into a clinical trial-led effort by the supplement recipient or to initiate a new trial leadership role. That said, the NOFO does allow a supported trainee or participant to gain research experience in a clinical trial as long as that clinical trial is led by an appropriate mentor or co-mentor. Practically, this means the supplement can be used to place and support a developing researcher in a setting where clinical trials are happening, but it cannot be used to make the supplement work itself a trial leadership vehicle.
Eligibility is centered on organizations that already hold certain NIH research grants (the parent award activity codes are specified in the full announcement). The notice explicitly excludes non-U.S. entities: foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by HHS Grants Policy) are not allowed under this NOFO. The opportunity is listed as discretionary funding, with a grant instrument type, in the health category (CFDA/Assistance Listing 93.103). The source data also lists small businesses among eligible applicants, which typically matters when a small business already holds an eligible NIH grant and seeks an administrative supplement under that award.
From a funding and timing standpoint, the opportunity was created on June 28, 2023, and the original closing date shown is May 7, 2026. The listed award ceiling is $500,000, which signals that supplement budgets can be substantial depending on the parent award, the proposed scope-aligned activities, and NIH institute/center policies. While the number of expected awards is not provided in the supplied source data, the program is broadly positioned as an NIH-wide mechanism to strengthen the biomedical and behavioral research pipeline by supporting salary, stipends, tuition, research experiences, and other allowable costs tied to the supplement candidate(s), as long as those costs directly advance the parent project and meet administrative supplement requirements.
In plain terms, this NOFO is best understood as a way for an NIH-funded research group to (1) expand and retain a more diverse research workforce by supporting individuals at multiple career stages, and/or (2) ensure continuity of the funded research when a PI needs disability-related support, without changing the core aims of the parent grant. The most important practical constraints are that the work must fit squarely within the existing project and that the supplement cannot be used to propose or lead a new independent clinical trial, even though mentored clinical trial experience is allowed.Apply for PA 23 189
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on 2023-06-28.
- Applicants must submit their applications by 2026-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Small businesses.
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| Single Source: Accelerating Medicines Partnership Schizophrenia (AMP SCZ): Clinical Trial Data Processing, Analysis, and Coordination Center (U24 Clinical Trial Not Allowed) Apply for RFA MH 24 151 Funding Number: RFA MH 24 151 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Accelerating Medicines Partnership Schizophrenia (AMP SCZ): Clinical High Risk for Psychosis Clinical Trial Network (U01 Clinical Trial Required) Apply for RFA MH 24 150 Funding Number: RFA MH 24 150 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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