Opportunity Information: Apply for PA 23 189
Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed), Funding Opportunity Number PA-23-189, is an NIH (and CDC-notified) administrative supplement program that provides add-on funds to existing, eligible NIH research grants so that current grantees can bring more people from diverse backgrounds into health-related research and support their training and career development. The basic idea is that the supplement is not a stand-alone grant for a brand-new project; it is extra support that must stay within the scientific scope of the already-funded parent award. Through these supplements, a funded lab or research team can recruit and support students, postdoctoral researchers, and certain eligible investigators, particularly individuals from groups that have been shown to be underrepresented in health-related research. In addition to the diversity-focused purpose, the program also covers a related need: it can provide supplemental support to a Program Director/Principal Investigator who has become disabled (or is disabled) and requires accommodations or other additional resources in order to continue working on the funded project.
A key restriction in this specific NOFO is the clinical trial limitation. This opportunity is structured for applicants who are not proposing to lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial under the supplement. In other words, you cannot use this administrative supplement to turn the parent grant into a clinical trial-led effort by the supplement recipient or to initiate a new trial leadership role. That said, the NOFO does allow a supported trainee or participant to gain research experience in a clinical trial as long as that clinical trial is led by an appropriate mentor or co-mentor. Practically, this means the supplement can be used to place and support a developing researcher in a setting where clinical trials are happening, but it cannot be used to make the supplement work itself a trial leadership vehicle.
Eligibility is centered on organizations that already hold certain NIH research grants (the parent award activity codes are specified in the full announcement). The notice explicitly excludes non-U.S. entities: foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by HHS Grants Policy) are not allowed under this NOFO. The opportunity is listed as discretionary funding, with a grant instrument type, in the health category (CFDA/Assistance Listing 93.103). The source data also lists small businesses among eligible applicants, which typically matters when a small business already holds an eligible NIH grant and seeks an administrative supplement under that award.
From a funding and timing standpoint, the opportunity was created on June 28, 2023, and the original closing date shown is May 7, 2026. The listed award ceiling is $500,000, which signals that supplement budgets can be substantial depending on the parent award, the proposed scope-aligned activities, and NIH institute/center policies. While the number of expected awards is not provided in the supplied source data, the program is broadly positioned as an NIH-wide mechanism to strengthen the biomedical and behavioral research pipeline by supporting salary, stipends, tuition, research experiences, and other allowable costs tied to the supplement candidate(s), as long as those costs directly advance the parent project and meet administrative supplement requirements.
In plain terms, this NOFO is best understood as a way for an NIH-funded research group to (1) expand and retain a more diverse research workforce by supporting individuals at multiple career stages, and/or (2) ensure continuity of the funded research when a PI needs disability-related support, without changing the core aims of the parent grant. The most important practical constraints are that the work must fit squarely within the existing project and that the supplement cannot be used to propose or lead a new independent clinical trial, even though mentored clinical trial experience is allowed.Apply for PA 23 189
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Supplements to Promote Diversity in Health-Related Research (Admin Supp Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.103.
- This funding opportunity was created on 2023-06-28.
- Applicants must submit their applications by 2026-05-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $500,000.00 in funding.
- Eligible applicants include: Small businesses.
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Frequently Asked Questions (FAQs)
What is PA-23-189 (Research Supplements to Promote Diversity in Health-Related Research)?
PA-23-189 is an NIH administrative supplement opportunity (CDC-notified) that provides additional funding to an existing, eligible NIH-funded research grant. The purpose is to help current grantees bring more individuals from diverse backgrounds into health-related research and support their research training and career development. The supplement is added onto (and must be tied to) a currently funded parent award.
Is this a stand-alone grant for a new project?
No. This is an administrative supplement, not a stand-alone award for a brand-new independent project. The proposed activities must remain within the scientific scope of the already-funded parent award.
What is the main goal of this supplement program?
The main goal is to strengthen and diversify the biomedical and behavioral research pipeline by supporting participation, training, and career development for individuals from groups shown to be underrepresented in health-related research, using add-on funds to an existing NIH grant.
Who is expected to benefit from the supplement funding?
The supplement is intended to support people being brought into an NIH-funded research environment, including students and postdoctoral researchers, and certain eligible investigators, particularly individuals from groups that have been shown to be underrepresented in health-related research.
Can this supplement also be used to support a PI with a disability?
Yes. In addition to the diversity-focused purpose, this NOFO can provide supplemental support to a Program Director/Principal Investigator (PD/PI) who is disabled (or becomes disabled) and needs accommodations or other additional resources to continue working on the funded project.
What does "Admin Supp Clinical Trial Not Allowed" mean for this opportunity?
This NOFO does not allow the supplement to be used to propose or lead an independent clinical trial, a clinical trial feasibility study, or an ancillary clinical trial under the supplement. The supplement cannot be used to convert the parent award into a supplement-led clinical trial effort or create a new clinical trial leadership role for the supplement-supported work.
Are any clinical trial-related activities allowed at all?
Yes, in a limited way. A supported trainee or participant may gain research experience in a clinical trial setting as long as the clinical trial is led by an appropriate mentor or co-mentor. The key distinction is that the supplement-supported individual can be mentored within an existing clinical trial environment, but the supplement itself cannot be used to initiate or lead a trial.
Do the supplement activities have to match the parent grant's aims?
Yes. The supplement must remain within the scientific scope of the already-funded parent award. It is intended to add capacity and training opportunities that directly advance the parent project, rather than change its core direction.
Who can apply for this administrative supplement?
Eligible applicants are organizations that already hold certain NIH research grants (the parent award activity codes are specified in the full announcement). The supplement is requested under an active parent award rather than through a new, independent application for a separate project.
Are foreign institutions eligible to apply?
No. Foreign institutions are not eligible to apply under this NOFO.
Can a non-domestic component of a U.S. organization apply?
No. Non-domestic components of U.S. organizations are not eligible to apply under this NOFO.
Are foreign components allowed on an application?
No. Foreign components (as defined by HHS Grants Policy) are not allowed under this NOFO.
Are small businesses eligible applicants?
The source information lists small businesses among eligible applicants. Practically, this matters when a small business already holds an eligible NIH parent award and is seeking an administrative supplement under that existing award.
Which agencies are associated with this opportunity?
This is an NIH opportunity and is described as CDC-notified in the provided information.
What is the Funding Opportunity Number (FON)?
The Funding Opportunity Number is PA-23-189.
What type of funding mechanism is this?
It is discretionary funding using a grant instrument type, offered as an NIH administrative supplement to an existing grant.
What is the Assistance Listing (CFDA) number for this opportunity?
The Assistance Listing (CFDA) number provided is 93.103.
What is the program area/category for this opportunity?
The opportunity is in the health category and is focused on health-related research workforce development and support within existing NIH-funded projects.
When was this opportunity created?
The opportunity was created on June 28, 2023.
What is the closing date shown for this opportunity?
The original closing date shown is May 7, 2026.
How much funding is available per award?
The listed award ceiling is $500,000. This indicates that supplement budgets can be significant, depending on the parent award, the scope-aligned activities proposed, and NIH institute/center policies.
Does the opportunity specify how many awards NIH expects to make?
No. The number of expected awards is not provided in the supplied source information.
What kinds of costs can the supplement support?
As described, the program is positioned to support costs such as salary, stipends, tuition, research experiences, and other allowable expenses tied to the supplement candidate(s), as long as those costs directly advance the parent project and meet administrative supplement requirements.
What is the simplest way to describe what this NOFO is for?
It is a way for an NIH-funded research group to add resources that (1) expand and retain a more diverse research workforce through supported research experiences and career development, and/or (2) help ensure continuity of the funded research when a PD/PI needs disability-related support, while keeping the work within the parent grant's scientific scope and not using the supplement to lead a new clinical trial.
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