Opportunity Information: Apply for RFA HD 18 003
Moving Beyond Standard Assessments: Applying Novel Tools to Assess Human Placental Structure and Function in Real Time (R01) is a National Institutes of Health (NIH) grant opportunity (Funding Opportunity Number RFA-HD-18-003; CFDA 93.865) focused on improving how researchers and clinicians evaluate the human placenta during pregnancy. The central purpose of the announcement is to support research that develops and applies new, safe technologies capable of measuring placental structure and function in real time while the pregnancy is ongoing. The emphasis is on approaches that work in vivo and are non-invasive or, if necessary, only minimally invasive, with the broader goal of moving beyond conventional or indirect assessments that may not capture placental performance as it changes across gestation.
The scientific and technical scope is framed around creating or adapting novel tools that can monitor placental development and function across pregnancy rather than relying solely on standard check-ins or end-point evaluations. In practical terms, the FOA is looking for methods that can repeatedly and safely assess the placenta while the fetus is developing, enabling a more dynamic and accurate picture of placental health. Although the announcement text does not list specific technologies, the intent clearly supports innovative measurement strategies that could provide real-time physiological, structural, or functional readouts of the placenta in a way that is feasible during routine pregnancy timelines and appropriate for human use.
This opportunity is offered as an R01 research project grant, which typically supports substantial, hypothesis-driven or technology-development research programs. It is categorized as a discretionary grant within the Health, Income Security and Social Services funding activity area. The stated award ceiling is $499,000, indicating the maximum amount expected per award under the terms of this specific announcement. The source data notes an expected awards field but does not provide a number, so the exact count of anticipated funded projects is not specified in the information provided.
Eligibility is broad and includes many types of U.S. organizations and governmental entities. Eligible applicants include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations other than federally recognized tribal governments; nonprofits with or without 501(c)(3) status (as long as they are not institutions of higher education); for-profit organizations other than small businesses; and small businesses. In addition, the FOA explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Historically Black Colleges and Universities (HBCUs); Hispanic-serving Institutions; Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; eligible federal agencies; U.S. territories or possessions; and certain non-U.S. participants, including non-domestic (non-U.S.) entities (foreign organizations) and regional organizations. This wide eligibility suggests NIH intended to attract interdisciplinary teams and diverse institutional participants, including those with specialized community ties or unique clinical/research infrastructures.
Key administrative details from the source data include an original closing date of 2017-03-31 and a creation date of 2016-12-15. Overall, the opportunity is best understood as a targeted NIH R01 call for innovation in placental assessment, prioritizing safe, real-time, in vivo measurement capabilities that can track placental structure and function throughout pregnancy and potentially improve understanding, monitoring, and outcomes related to placental health.Apply for RFA HD 18 003
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Moving Beyond Standard Assessments: Applying Novel Tools to Assess Human Placental Structure and Function in Real Time (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on 2016-12-15.
- Applicants must submit their applications by 2017-03-31. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $499,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is the name of this grant opportunity?
The opportunity is titled "Moving Beyond Standard Assessments: Applying Novel Tools to Assess Human Placental Structure and Function in Real Time (R01)."
Which agency is offering this funding opportunity?
This is a National Institutes of Health (NIH) grant opportunity.
What is the Funding Opportunity Number (FOA number)?
The Funding Opportunity Number is RFA-HD-18-003.
What is the CFDA number for this opportunity?
The CFDA number listed is 93.865.
What is the main purpose of this FOA?
The central purpose is to support research that develops and applies new, safe technologies to measure human placental structure and function in real time during an ongoing pregnancy.
What problem or gap is NIH trying to address with this FOA?
The FOA is focused on moving beyond conventional or indirect assessments that may not reflect how placental performance changes over gestation. It prioritizes approaches that can track placental health dynamically and more accurately during pregnancy.
What type of grant mechanism is used?
This is an R01 research project grant.
What kind of research does an R01 support in this context?
Based on the FOA description, the R01 is intended to support substantial research programs, including hypothesis-driven studies and/or technology-development efforts aimed at real-time, in vivo assessment of placental structure and function.
What is meant by "real time" assessment in this announcement?
In this FOA, "real time" refers to technologies and methods that can measure placental structure and function during pregnancy as it is happening, rather than relying only on end-point evaluations or infrequent standard check-ins.
Does the FOA emphasize in vivo measurements?
Yes. The emphasis is on approaches that work in vivo (in the living human body) during pregnancy.
Are non-invasive methods required?
The FOA emphasizes non-invasive approaches, and allows minimally invasive methods if necessary, as long as the technologies are safe and appropriate for use during pregnancy.
Does the FOA specify particular technologies that applicants must use?
No. The information provided does not list specific technologies. Instead, it emphasizes innovative measurement strategies capable of providing real-time physiological, structural, or functional readouts that are feasible for human use during pregnancy.
What aspects of the placenta are the tools expected to measure?
The FOA focuses on placental structure and function, with the intent that tools provide structural and/or functional readouts and enable monitoring of placental development and performance across gestation.
Does this opportunity focus on repeated assessments over time?
Yes. A key theme is the ability to repeatedly and safely assess the placenta throughout pregnancy to capture changes over gestation.
Is the goal to replace standard assessments?
The FOA is aimed at moving beyond standard or indirect assessments by developing and applying novel tools that can better capture placental performance in real time. It does not state that standard assessments must be replaced, but it clearly prioritizes going beyond them.
What is the maximum award amount (award ceiling)?
The stated award ceiling is $499,000 (the maximum amount expected per award under this announcement).
How many awards does NIH expect to make?
The source data includes an "expected awards" field, but it does not provide a number. Based on the information provided, the anticipated count of funded projects is not specified.
What is the funding activity area?
The opportunity is categorized within the Health, Income Security and Social Services funding activity area.
What type of funding is this considered?
It is categorized as a discretionary grant.
Who is eligible to apply?
Eligibility is broad and includes many U.S. organizations and governmental entities, including:
- State governments
- County governments
- City or township governments
- Special district governments
- Independent school districts
- Public and state-controlled institutions of higher education
- Private institutions of higher education
- Federally recognized Native American tribal governments
- Public housing authorities and Indian housing authorities
- Native American tribal organizations other than federally recognized tribal governments
- Nonprofits with 501(c)(3) status (other than institutions of higher education)
- Nonprofits without 501(c)(3) status (other than institutions of higher education)
- For-profit organizations other than small businesses
- Small businesses
Are minority-serving institutions and community-based organizations eligible?
Yes. The FOA explicitly highlights eligibility for Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Historically Black Colleges and Universities (HBCUs); Hispanic-serving Institutions; Tribally Controlled Colleges and Universities (TCCUs); and faith-based or community-based organizations.
Can federal agencies apply?
Yes. The FOA includes eligible federal agencies among the additional eligible applicant categories.
Are U.S. territories or possessions eligible to apply?
Yes. U.S. territories or possessions are explicitly listed among eligible applicant categories.
Are foreign (non-U.S.) organizations eligible to participate?
Yes. The FOA includes certain non-U.S. participants, including non-domestic (non-U.S.) entities (foreign organizations) and regional organizations.
What is the application closing date listed for this opportunity?
The original closing date listed is 2017-03-31.
When was this opportunity created?
The creation date listed is 2016-12-15.
What is the overarching objective for placental monitoring according to this FOA?
The objective is to enable safer, more dynamic assessment of placental health by measuring placental structure and function in real time during pregnancy, potentially improving monitoring, understanding, and outcomes related to placental health.
Does the FOA mention clinical feasibility during routine pregnancy timelines?
Yes. The description emphasizes that methods should be feasible during routine pregnancy timelines and appropriate for human use.
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