Opportunity Information: Apply for RFA DK 22 504
This funding opportunity is a National Institutes of Health (NIH) cooperative agreement that supports the continuation of the Chronic Kidney Disease in Children (CKiD) Consortium through a limited competition restricted to the two existing Clinical Coordinating Centers (CCCs) already participating in the study. The lead NIH institute is the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), working in collaboration with the National Heart, Lung, and Blood Institute (NHLBI) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The intent is not to launch a brand-new study, but to maintain and extend the ongoing, prospective pediatric chronic kidney disease cohort infrastructure and follow-up, preserving continuity in recruitment, data collection, and long-term participant evaluation.
The award mechanism is a U01 cooperative agreement (Funding Opportunity Number RFA-DK-22-504), which means the NIH will have substantial scientific and programmatic involvement in the conduct of the project, beyond what is typical for standard research project grants. The announcement specifies "Clinical Trial Not Allowed," indicating the supported work is centered on observational follow-up, cohort maintenance, and related consortium activities rather than testing interventions in a clinical trial framework. The CCCs are expected to continue evaluating currently enrolled participants, recruit and enroll new participants as appropriate for the cohort, and operate as part of a coordinated consortium rather than as independent sites.
A central feature of the opportunity is required collaboration with the consortiums existing shared resources, specifically the Data Coordinating Center (DCC) and the Central Biochemistry Laboratory (CBL). In practice, this means the CCCs are expected to follow common study-wide protocols, harmonized procedures, and shared governance for things like participant assessments, sample collection and processing, data submission and quality control, and coordinated reporting. The continuation structure emphasizes teamwork and standardization across sites so that longitudinal clinical measures, laboratory values, and outcomes remain comparable over time and across participants.
Eligibility is intentionally narrow. Only the current recipients funded under the prior CKiD clinical coordinating center announcement (RFA-DK-17-502) are eligible to apply under this continuation FOA. While the general eligible applicant type listed includes public and state-controlled institutions of higher education, the limited competition language effectively restricts applicants to the two incumbent CCC awardees. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to apply; however, foreign components as defined by the NIH Grants Policy Statement are allowed, which typically means certain discrete elements of work may be conducted outside the U.S. under specific conditions while the applicant organization remains U.S.-based and compliant with NIH policy.
The opportunity falls under the NIH discretionary funding category and is associated with CFDA numbers 93.837, 93.847, and 93.865. The posting lists an award ceiling of $925,000. The FOA was created on July 15, 2022, and the original application closing date was October 26, 2022. Overall, the program is designed to ensure that the CKiD Consortium can continue its prospective study operations with stable clinical coordinating capacity, ongoing participant follow-up, and continued recruitment, while maintaining tight integration with centralized data and laboratory coordinating functions to support high-quality, longitudinal pediatric kidney disease research.Apply for RFA DK 22 504
- The National Institutes of Health in the food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "Limited Competition for Continuation of the Prospective Study of Chronic Kidney Disease in Children Clinical Coordinating Centers (U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.837, 93.847, 93.865.
- This funding opportunity was created on 2022-07-15.
- Applicants must submit their applications by 2022-10-26. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $925,000.00 in funding.
- Eligible applicants include: Public and State controlled institutions of higher education.
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